Correlación entre infección por esptein-barr virus y severidad de la enfermedad periodontal. Clínica UCSG A-2018

Abstract

Introduction: The role of bacteria in the etiology of periodontal disease is well-known, however, their mere presence does not fully explain the stomatological and pathological findings associated with the disease. It has been proposed that the latter derive mostly from the interaction between viruses and bacteria, in which EBV infection has been associated with the most severe clinical circumstances of the same. Objective: To determine whether the infection of Epstein - Barr virus in the affected periodontal sites correlates with the severity of the periodontal disease. Materials and methods: A cross-sectional study comprised of 100 patients between 20 and 80 years old, who were diagnosed with periodontal disease and treated at the dental clinic of the UCSG. The patients were subjected to sampling through the collection of subgingival plaque of affected periodontal sites. The samples were analyzed through Real time PCR. The data obtained was collected in an Excel database. Correlation between Epstein-Barr virus infection and severity of periodontal disease was determined via Chi-squared test. Results: A negative correlation was obtained between EBV infection and type of periodontal disease (chi square 0.08 1df p = 0.780), as clinical attachment level (chi square 1.34 2df p = 0.511). However, correlation was demonstrated between EBV infection and probing depth. (Chi square 7.35 2df p = 0.025). Conclusion: There is no significant correlation between the cases studied, positive for EBV and severity of periodontal disease