Manejo y resistencia antibiótica de infecciones por pseudomona aeruginosa durante el periodo septiembre 2016 – diciembre 2019 en el hospital de especialidades Teodoro Maldonado Carbo; Guayaquil, Ecuador.

Abstract

Introduction: Pseudomona aeruginosa infections is one of the most critical and serious complications within the hospital setting, which represents a great diversity of manifestations, depending on the affected area or region. In addition to being a potentially virulent pathogen, it has great resistance to various types of antibiotics, which is why clinical evaluation is necessary to determine the different types of prognosis, given that it increases mortality when it is added to a pathology already frequent (comorbidities). The risk runs from prematurely born infants to the elderly with an unfavorable history. The most specific diagnostic method for this type of pathogen is blood culture, while maintaining the patient with empirical treatment, after taking it for culture and obtaining the result of the MIC (minimum inhibitory amount) which will determine us the most optimal antibiotic for the eradication of this pathogen. Materials and methods: A cross-sectional, observational and descriptive cohort study was carried out in which a total of 123 patients admitted from September 2017 to December 2019 and who had infection caused by Pseudomona Aeruginosa in the last 3 months within the facilities and services of the Teodoro Maldonado Carbo Hospital. Results: Previously applied the inclusion and exclusion criteria of our study as a single source: Hospital de Especialidades Teodoro Maldonado Carbo; It is determined that the resulting sample is 123 patients with a diagnosis of Pseudomonas Aeruginosa infection, of which the following result is given to the variable: Death of the patient at discharge or at the end of follow-up represented as "Mortality", with 60 cases corresponding to living patients (48.8%); in contrast to 63 cases of deceased patients (51.2%) where death was also classified by sex, with 43 male patients and 20 female patients with measures of central tendency of: mean (31.5 years), median (31.5 years) and fashion (60 years). Conclusions: Pseudomona Aeruginosa in elderly male patients with an average age of 60 years, who present comorbidities and who are admitted to hospital facilities at a certain time, where they require mechanical ventilators, have a higher risk of mortality caused by the prolongation of both the use of the mechanical ventilator and the installation time in the area. In addition, the resistance that Pseudomonas Aeruginosa has generated within the hospital area, which promotes the failure of the first and second lines of antibiotic therapy used.