Incidencia de síndrome de Cushing en pacientes del Hospital Teodoro Maldonado Carbo en el periodo enero 2016 – diciembre 2020.

Abstract

INTRODUCTION: Cushing´s Syndrome, a clinical disorder caused by a prolonged increase in steroid hormones, called hypercortisolism. (1) In general, the cause of hypercortisolism is dependent and not dependent on adrenocorticotropic hormone (ACTH); having 80% of Cushing in a dependent way caused by increased secretion of ACTH either by pituitary tumors, as well as excessive primary secretion of cortisol; and with 20% in a non-dependent manner, product of the administration of exogenous corticosteroids and tumors or hyperplasia of the adrenal gland. (2) (3). OBJECTIVE: To identify the incidence of Cushing´s syndrome at the Teodoro Maldonado Carbo Hospital in the period January 2016 to December 2020. METHODOLOGY: we carried out a retrospective study, whose population was 359 patients, and with a sample of 92 patients who met the criteria of inclusion and exclusion. RESULTS: with the analysis of the data collected, it is evidenced that the reported cases of Cushing´s Syndrome due to pharmacological causes are 53.3% of the cases, followed by pituitary adenoma with 22.8% of the cases, as well as without etiological report 22.8% of the cases. CONCLUSION: The most frequent cause of Cushing´s Syndrome in the patients under study is due to drugs, likewise the male sex and age between 40 to 50 years and a high body mass index among the risk factors, the Symptoms may or may not be evident among the cases studied.