Incidencia de complicaciones de la terapia biológica en pacientes diagnosticados con artritis reumatoide en el Hospital Teodoro Maldonado Carbo durante el periodo enero 2019 – diciembre 2021.

Abstract

Objectives: To determine the incidence of complications caused by biological therapy in patients with rheumatoid arthritis at Teodoro Maldonado Carbo Hospital. Methodology: Non-experimental retrospective cross-sectional observational study. 289 patients obtained through the inclusion and exclusion criteria were included. The group studied had ages between 21 and 92 years of age Results: A third of the total population had some complication, representing a rate of 27.7%. Within this group, it was found that the most frequent complication with 39% was headache, followed by infections with 27% and vomiting in third place. Among the results, the drug with the highest rate of complications was Etarnecept with 26.47% and Infliximab with 13.97%. Conclusions: The use of biological drugs for the treatment of rheumatoid arthritis and its relationship with the appearance of complications, despite not being frequent, represents a third of the population studied. The appearance of these effects will depend on the drug used in the therapy.