Genotipos de alto y bajo riesgo en lesiones bucales en pacientes con VPH.

Abstract

Introduction: Human papillomavirus is an epitheliotropic DNA virus, this virus causes skin or mucosal proliferation, generally manifested as papillary warty lesions, either in the form of benign lesions or as premalignant and malignant lesions in the oral cavity, as well as in latent form where the papilloma virus persists in the host cells without clinical manifestation. evident. Objective: Determine the prevalence of high and low risk genotypes of HPV in a group of patients from the pathology laboratory Dr. Gustavo Rubio Coronel. Materials and methods: A retrospective crosssectional study of a descriptive, non-experimental type was carried out; where the data were collected through the analysis of histopathological examinations performed in the Dr. Gustavo Rubio Coronel pathology laboratory. A universe of 285 histopathological examinations was obtained, from which a sample of 152 examinations of patients who met the established inclusion and exclusion criteria was subtracted. Results: The most prevalent genotypes in our study were HPV 6,11,16, predominating in males with coinfections of other serotypes; Of the sample analyzed, it was observed that genotypes from the low-risk group were mostly present. Conclusion: In the present study group, a higher prevalence of benign and potentially malignant lesions in the oral cavity has been demonstrated, mainly generated by low-risk genotypes 6,11 and high-risk genotypes 16, which are evident within concomitant infections with other serotypes. with greater malignant potential.