Insulinoresistencia en pacientes con síndrome de ovario poliquístico en el Hospital Teodoro Maldonado Carbo en el periodo 2023-2024.

Abstract

Introduction: Polycystic ovary syndrome (PCOS) is a gynecological disorder characterized by menstrual irregularities, hyperandrogenism, and multiple cysts on the ovaries. This hormonal imbalance significantly affects the quality of life of women of reproductive age. Insulin resistance plays a key role in the development of complications, and the HOMA-IR index is used to detect it. Objective: To estimate the prevalence of insulin resistance in patients with PCOS at the Teodoro Maldonado Carbo Hospital during the period 2023-2024. Methodology: This is a retrospective observational study with a sample of 143 patients with PCOS, aged 18 to 40 years. Results: The mean age was 29.72 ± 4.5 years. 42.65% of the patients were obese. The mean HOMA-IR index was 3.09 ± 0.6. A positive correlation was found between body weight and the development of insulin resistance. The prevalence of insulin resistance in PCOS was 24.47%. The most frequent complications were infertility (42.66%), endometriosis (11.19%), and recurrent miscarriages (6.30%). Conclusions: Obesity is associated with insulin resistance in PCOS.