Uso PCR como determinante de antibioticoterapia a realizar en neonatos ingresados con diagnóstico de sepsis neonatal en el Hospital General Liborio Panchana Sotomayor; octubre del 2016 hasta mayo del 2017.

Abstract

Introduction: In Latin America, there are many researches on the different aspects of neonatal sepsis, highlighting those performed in Brazil in 2015 about its diagnosis through laboratory markers in umbilical cord as well as clinical practice guidelines published in other countries in the region, such as Ecuador. Neonatal sepsis is one of the main causes of neonatal intensive care and one of the major causes of neonatal death in both developed and developing countries. Objectives: To determine the use of complete blood cytometry and CRP as referents for antibiotic therapy in neonates admitted with diagnosis of neonatal sepsis in the general hospital Liborio Panchana Sotomayor from October 2016 to May 2017 Materials and Methods: This is a non-experimental, descriptive, cross-sectional study composed of 59 patients who were evolved under the ICD 10 corresponding to the diagnosis of Neonatal Sepsis, in the period between October 2016 and May 2017. Results: The prevalence of Neonatal Sepsis was 38.6%. 72.9% presented in newborns of male sex. The most frequently used antibiotic regimen was Ampicillin + Gentamicin in 83% and it was observed that the PCR was performed in 64% of cases admitted under the diagnosis of Neonatal sepsis, being positive in 18% of the cases. In 72% of the positive cases, it was necessary to change the antibiotic scheme. Conclusions: Neonatal sepsis was the most frequent reason for admission, with a positive association between male sex and the risk of developing neonatal sepsis. The most commonly used antibiotic regimen is Ampicillin + Gentamicin. A positive association was found between the PCR positive result and the change in the antibiotic scheme used.