Eficacia de los niveles de albúmina como marcador de mortalidad en pacientes sépticos en el Hospital Teodoro Maldonado Carbo del 1 de enero al 31 de diciembre de 2017.

Abstract

Introduction: Sepsis is the potentially fatal organic dysfunction caused by a dysregulated host response to infection, and one of the most frequent pathologies in our environment with a high mortality rate, based on the recovery of glycocalyx through albumin serum is intended to benefit the patient of the HTMC’s Critical Care Units. Objective: To analyze the effect of albumin levels on the mortality of septic patients at the Critical Care Units of Teodoro Maldonado Carbo Hospital. Methodology: Quantitative, prospective, observational and cohort research was carried out in the critical care areas of Teodoro Maldonado Carbo Hospital in Guayaquil city, during the period from January 1 to December 31, 2017. Results: 235 patients of the study, 136 (57.87%) were male and 99 (42.13%) were female. Of which 69 men died (50.74%) as well as 60 women (60.61%). The Gram-negative bacteria predominated in cultures, being the Klebsiella Pneumoniae the most isolated one, and correlating with this the main focus of infection was the pulmonary, although the one of greater mortality is the intra-abdominal. Serum albumin levels below 3 g / dL predict with significance when it is <3 g/dL (Pr = 0.000). Conclusion: For each gram of serum albumin that decreases the mortality of septic patient increases by 13.42% in a significant way. Above all, in those with a history of type 2 diabetes mellitus and chronic renal failure are predicted to develop this pathology.