Análisis de supervivencia y mortalidad en pacientes sometidos a trasplante de precursores hematopoyéticos en la Unidad de Trasplantes del Instituto Oncológico Nacional “Dr. Juan Tanca Marengo”, SOLCA en la ciudad de Guayaquil, desde el año 2006 al 2016.

Abstract

Hematopoietic cell transplantation (HSCT) is a useful therapeutic measure for pathologies that alter hematopoiesis, allowing the restoration of bone marrow function and whose scope is limited for Latin American countries. It is important to evaluate the results of it in our environment, because it is a technique in development. This is a retrospective study, conducted at the Dr. Juan Tanca Marengo Oncological Institute, which included N = 158, we analyzed the survival and mortality of patients submitted at this treatment, in the period 2006 -2016. The main cause of mortality related to transplantation (MRT) was graft-versus-host disease (GVHD) in 8.23%, and the main cause of mortality unrelated to transplantation (MURT) was relapse (14.53%), presented mostly in acute lymphoid leukemia. Survival was 64.82%, being higher in autologous type transplants (p <0.05), with remission in 50.63% of patients. We must emphasize that the number of transplants has been gradually increasing over the years, however it has shown optimal results, comparable to studies conducted in developed countries.