Correlación del signo de doble contorno con los niveles de ácido úrico en población sana y en pacientes en hemodiálisis.

Abstract

Introduction: Gouty arthritis is a common disease worldwide related to hyperuricemia, a common finding in patients with chronic kidney disease and metabolic syndrome. The double contour echographic sign is considered pathognomonic of gouty arthritis, but its presence in asymptomatic hyperuricemic patients has been little studied. Objective: To determine the presence of a double contour sign in a healthy population and in dialysis patients without a history of gouty arthritis. Methodology: Cross-sectional, observational and descriptive study. Individuals with no history of gouty arthritis or kidney disease and patients who underwent hemodialysis at the IEDYT without a history of gouty arthritis were recruited. The participants were taken a blood sample to measure the level of uric acid and ultrasound of the MTFs and knees were performed to look for the presence of a double contour sign. These findings were correlated with each other and with the variables of age, sex and time of dialysis. Results: A total of 53 individuals were recruited: 23 healthy and 30 on dialysis. For dialysis patients, the average level of uric acid was 5.78 mg / dl, whereas for healthy individuals, the average level was 4.12 mg / dl. Of all the individuals, 50 had at least one joint with a double positive contour sign. There was no greater risk of having a double contour sign for the dialysis population (OR 0.138, 95% CI 0.0302 to 0.0627). Neither was a correlation found between hyperuricemia and the presence of a double contour sign. Conclusions: An important prevalence of double contour sign was found in young individuals without risk factors. This finding should be studied in the future due to the potential impact on the health of our population.