Valor pronóstico de la eosinopenia, proteína C reactiva y procalcitonina en pacientes sépticos de la Unidad de Cuidados Críticos del Hospital Teodoro Maldonado Carbo de la ciudad de Guayaquil del 1 de enero del 2018 al 1 de julio del 2018.

Abstract

Introduction: Sepsis is a syndrome that consists of a severe infection triggered by a variable host systemic response that produces generalized tissue damage, there are several biomarkers that are altered in response to it and are increasing or decreasing according to the patient's clinical evolution, these are C-reactive protein (CRP), Procalcitonin (PCT) and eosinopenia. Objective: Our objective was to use the biomarkers to determine the prognosis of patients with sepsis in the critical care unit. Materials, Methods, Design: Quantitative, prospective, analytical, observational and cohort research. We reviewed the medical records of all patients with the ICD10 codes related to sepsis that were found in the Critical Care Units of adults belonging to the Hospital Teodoro Maldonado Carbo (HTMC). Results: In the study, 84 patients of the HTMC of the critical care unit with a diagnosis of sepsis were evaluated, of which 47 were men and 37 women, the total mortality was 54.76%. Women had a mortality of 64.86% compared to men 46.81%. There was eosinopenia in 52.38% of the patients, and had a relation with the mortality of 63.64% (p = 0.08), there was a PCT> 2 ng / ml in 35.71% of the patients with a mortality of 80% (p = 0.01), in the same way 38 patients had a CRP> 20 mg / l of which 65.79% died (p = 0.06). The comorbidity with the highest percentage was HBP with 63.09%. Conclusion: Sepsis has a high mortality rate and is higher in females, PCT is the best biomarker to evaluate the survival prognosis of the septic patient, although the relationship between CRP / Eosinopenia and Mortality is not significant, it has a great trend, the most frequent comorbidity was HBP