Resistencia antimicrobiana en klebsiella pneumoniae en el Hospital Teodoro Maldonado Carbo, incidencia, tipos de infecciones registradas y tratamiento recibido en período de enero del 2016 a diciembre del 2016.

Abstract

OBJECTIVE: To record the types of Klebsiella pneumoniae infections in patients treated at the HTMC between October 2016 and December 2016 and determine whether or not antimicrobial resistance exists. METHODOLOGY: Observactional, descriptive, retrospective and cross-sectional study, not experimental. The sample size consisted of 149 patients without distinction of sex or age, with cultures positive for Klebsiella pneumoniae infection. RESULTS: 72% of the patients were male, the age range was from 0 to 97 years with an average of 63.3 years. And the average hospital stay was 42.8 days with a range of 0 to 178 days. The mortality rate in the patients studied was 63%. The service of origin where the patients attended when the sample was taken with the highest percentage of patients contributed were the areas of hospitalization of the hospital: 70 (47%), followed by the intensive care area: 63 (42%). Among the underlying diseases prior to taking the sample for culture, hypertension was the most frequent with 88 cases (59%). The most frequent type of infection that motivated the study was pneumonia with 68 cases (46%). The site from which the most common sample was obtained was by tracheal aspirate: 51 (34%). The use of previous antibiotic was evidenced in 117 cases (79%). The drug that showed the highest sensitivity was colistin with 88% and ampicillin with the highest resistance, with 97% 94% producing KPC. Finally, the most used antibiotic treatment was the combination colistin + meropenem (11%) followed by meropenem in monotherapy (8%).