Impacto de la farmacovigilancia sobre las reacciones adversas relacionadas con medicamentos documentadas en el Hospital “Teodoro Maldonado Carbo” y Hospital de Infectología “Dr. José Daniel Rodríguez Maridueña”. 2018 - 2019.

Abstract

Introduction: pharmacovigilance is defined as a science and activities related to the detection, evaluation, understanding and prevention of adverse drug reactions. In our country, the literature related to this topic applied in health establishments is limited. Objective: Analyze the impact of pharmacovigilance on adverse reactions related to drugs documented at Hospital “Teodoro Maldonado Carbo” and Hospital de Infectología "Dr. José Daniel Rodríguez Maridueña." 2018 – 2019. Materials and methods: a descriptive, observational, cross-sectional prevalence study. Carried out in 2 hospitals in Guayaquil, Ecuador with a duration of 13 months between 2018 and 2019. The information was collected from the reports of medical records and yellow cards. Results: The majority of reported cases (80%) were from the Hospital de Infectología (HI). 41 (54%) patients were of hospital origin and 34 (45%) were ambulatory. The combination of Tenofovir, Emtricitabine and Efavirenz were the drugs mostly associated with adverse reactions. An 88% resolution of the adverse event was reported by the Hospital de Infectología (HI) versus 20% (HTMC). Conclusions: There are more and more health establishments in Ecuador that implement the pharmacovigilance system in their facilities. This system allows units such as the HI to not only detect the cause or association of the adverse event but also its possible early resolution, improving the adherence of the patient to its treatment.