Caracterización de pacientes con nefritis lúpica del Hospital de Especialidades Teodoro Maldonado Carbo en el período 2016 – 2018.

Abstract

Introduction: Lupus Erythematous Systemic (LES) is a chronic inflammatory disease that compromises various organs such as the kidney. According to various studies almost 50% of the patients with LES present this kidney injury. In Ecuador currently there is no registered data about how this Lupus Nephritis (LN) presents itself, due to the lack of studies. Objective: Characterization of patients with Lupus Nephritis in Teodoro Maldonado Carbo Specialties Hospital during 2016 – 2018. Methodology: We used a retrospective longitudinal study. 185 patients matched our inclusion criteria of having a diagnosis from a specialist in nephrology or rheumatology with the CIE 10 codification (M32, M32.1, M32.8 o M32.9). Results: Female gender was 81. Ages between 18 – 45 years were 74.1% with a mean age of 36 years old. Type of nephritis class II was 25.4%, class III was 26.5%.class IV was 33% and class V was 12.4%. Treatment with Mycophenolate Mofetil monotherapy was 69.2%. AntiDNA debut was positive in 64.9% and in the most recent antiDNA was positive 61.1%. Both C3 and C4 decrease were positive in 59.5% in debut. Conclusions: LN occurs more in females. 36 years old is the mean age of this affection. The most common type of Nephritis was class IV. The most used treatment was Mycophenolate Mofetil monotherapy. All the laboratory parameters, at the debut recollection were positive.