Parámetros de coagulación e índice plaquetario como factores predictores de preeclampsia en pacientes embarazadas del Hospital General IESS Quevedo, año 2017- 2018.

Abstract

Background: preeclampsia (PE) is a disorder of pregnancy that affects all women worldwide and causes serious complication, including fetal maternal death. PE is defined as a blood pressure greater than 140/90 and proteinuria more than 300mg/24h at 20th weeks of gestation. Objectives: we wanted to link the platelets count and the coagulation parameters as predictive markers in the presentation of preeclampsia. Methods: this is a retrospective study. We used the clinic history of 109 patients divided into two groups: women with preeclampsia and healthy women, using variables such as platelets and coagulation time. The results were obtained with ROC curves and predictive values of the parameters with greater significance. Results: the VPM (mean platelet volume) and PDW (plaquetary distribution wide) were more significant in the third trimester (s 81,8% - e 65,1% y s 90.9% - e 14.3%, respectively), giving a higher negative predictive value for the presentation of preeclampsia. The positive predictive values weren’t conclusive in both platelets and coagulation time. Conclusion: we conclude that a normal value in VPM and PDW excludes the presentation of preeclampsia (negative predictive value) but is not useful as predictor parameter for de onset of preeclampsia.