Conteo plaquetario como factor predictor de mortalidad en sepsis en la UCI del Hospital Luis Vernaza en el periodo de junio a diciembre del 2018.

Abstract

Background: Platelets are cells with an important role in the maintenance of hemostasis and coagulation. Thrombocytopenia is a platelet count <150,000/mm3 and constitutes one of the most common hemostatic disorder in the ICU with a prevalence of 50%, as well one of the most serious complications and frequent in sepsis. More than 50% of the patients with sepsis develop this disorder, increasing the risk of 1,4 +- 2,1 times higher mortality. Objective: To study the presence of thrombocytopenia as a predictive factor of mortality in patients with the diagnosis of sepsis in the ICU of Luis Vernaza Hospital. Materials and Methods: An observational and analytical cohort study was conducted. Patients from the ICUs of the Luis Vernaza Hospital who entered during the period from June to December 2018 and met the inclusion criteria were included. The levels of platelets and procalcitonin were measured at the beginning and end of the stay in the ICU, the septic focus and the presence or not of comorbidities. Results: 65.5% of the patients had thrombocytopenia during their stay and 67% of them died. The septic focus was most frequently the abdominal focus and 68% had comorbidities, the most frequent being hypertension. Conclusion: The presence of thrombocytopenia in patients with sepsis admitted to the ICU leads to a higher mortality tendency compared to those who maintain normal platelet levels. However, the small size of the population did not allow to obtain results with statistical significance.