Evaluación del uso de los inhibidores de la bomba de protones en pacientes entre 20 y 60 años hospitalizados por más de 48 horas en el Hospital General del Norte de Guayaquil IESS los Ceibos, periodo 2017-2018.

Abstract

Introduction: Proton pump inhibitors are drugs that act by blocking the secretion of gastric acid by irreversibly binding with the ATPase pump of hydrogen and potassium. Indications for use are: complicated gastroesophageal reflux disease, Barret's esophagus, peptic ulcer disease, ulcers associated with NSAIDs, Zollinger-Ellison syndrome and Helicobacter pylori eradication. Objective: To evaluate the use of proton pump inhibitors in patients between 20 and 60 years hospitalized for more than 48 hours at the General Hospital of the North of Guayaquil IESS Los Ceibos, period July 2017 - July 2018. Material and method: A retrospective, observational and analytical study was carried out. The universe used were clinical records of hospitalized patients at the General Hospital of the North of Guayaquil IESS Los Ceibos during the period July 2017 - July 2018; A sample of 384 patients was used. Results: In the present study it was found that in 62.00% of hospitalized patients received PPI inappropriately. A significant tendency to misuse PPI was detected in patients with low risk and the opposite with high risk patients. Among the distribution of the population, it was obtained that most of them were in the trauma / orthopedics service (20.30%), followed by general surgery (20.10%) and internal medicine (17.70%). Conclusions: It was concluded that in 62.00% of the patients hospitalized at the IESS Los Ceibos Hospital, PPIs were used improperly based on gastrointestinal risk stratification.