Correlación entre los niveles séricos de la glicoproteína CA 125 y los diferentes estadios de severidad de la endometriosis en el Hospital de Especialidades Teodoro Maldonado Carbo en el período comprendido entre enero 2017 - septiembre 2019.

Abstract

Introduction: Endometriosis is a very prevalent disease in women, the delay in its diagnosis creates an unfavorable environment in those affected, so a tool is necessary to raise the degree of suspicion and perhaps indicate its degree of severity. Objective: To correlate the serum levels of the tumor marker Ca 125 with pelvic endometriosis and with its severity stages in patients who underwent surgery at the Teodoro Maldonado Carbo Specialty Hospital during the period from January 2017 to September 2019. Materials and methods: The design of the present study is observational, retrospective, transversal and analytical. It was performed in 105 patients who underwent surgery at the Teodoro Maldonado Carbo Specialty Hospital in the period between January 2017 and September 2019. We sought to establish the correlation between the value of Ca 125 before surgery and the stages of severity of endometriosis, for which the Spearman correlation and its Rho value were used. One-way analysis of variance (ANOVA) was also determined between these 2 variables. The relationship between other variables was studied using parametric tests (T test for independent samples, T test for related samples) and non-parametric tests (Kruskal-Wallis H test), according to the distribution of the data. Results: The mean age of the study patients was 36.6 years. With 44.76%, stage IV was the most frequent, followed by stage III with 28.57% of cases. It was observed that there is a correlation between the preoperative value of Ca 125 and the different stages of severity (p: 0.000). Its degree of correlation was good (Rho: 0.753). Conclusion: There is a correlation between the preoperative level of the tumor marker Ca 125 and the degree of severity of endometriosis.