Comparación de la citotoxicidad de los cementos obturadores biocerámicos y a base de resina epóxica. Revisión sistemática.

Abstract

Introduction: Currently, there are several types of endodontic sealers with different compositions available on the market. In vitro and in vivo studies have shown that they can cause cytotoxic effects on periapical tissues which contribute to delayed healing and could modify the normal endodontic treatment process. Objective: To analyze the types of cells studied, time, stages and degrees of cytotoxicity of bioceramic and epoxy resin-based sealers. Materials and methods: Literature review study, with a cross-sectional qualitative approach, with a descriptive and retrospective type of research, consisting of a total of 55 articles for data collection, these used documents from a time interval between 1982 - 2020. Results: First the types of cells that were studied were analyzed, in which 1 HGF-1 cells have the highest prevalence with 37.5%, the most studied observation period in these articles was between 2 - 7 days, the stage in which cytotoxicity begins is from the fresh mixture, with respect to the level of cytotoxicity we have that bioceramic sealers have a lower degree compared to those based on epoxy resin. Conclusion: After the present bibliographic review it can be concluded that bioceramic sealers are less cytotoxic than those based on epoxy resin.