Influencia de la hipocloremia en la mortalidad intrahospitalaria de pacientes con insuficiencia cardiaca en el Hospital de Especialidades Teodoro Maldonado Carbo en el periodo de junio 2018 a mayo 2019.

Abstract

Introduction: Chloride is the major anion of the extracellular fluid, its low serum levels, hypochloremia, are a common electrolyte abnormality in patients with Heart Failure (HF). Recently, an association between low serum chloride and adverse outcomes in patients with HF has been suggested by several studies. This association is independent of the HF phenotype and more established prognostic markers (NT-proBNP). Objective: Evaluate the influence that low serum chloride, measured within 24 hours of hospital admission, has over the in-hospital mortality of patients with Heart Failure. Methods: We performed an observational-retrospective analytical study by reviewing the electronic clinical records of patients with HF treated at Hospital de Especialidades Teodoro Maldonado Carbo from June 2018 to May 2019. Results: 89 patients with diagnosis of HF were included in this study. The prevalence of hypochloremia was 13.5% in the study population, and the in-hospital mortality rate in this group of patients was significantly higher (58.3%) (p<0.05) in comparison with patients with normo and hyperchloremia. Conclusion: There is an association between low serum chloride and a higher in-hospital mortality rate in patients with HF.