Tiroiditis de hashimoto : factor pronóstico en pacientes con carcinoma papilar en tiroides en el Hospital Solca de Guayaquil, 2014 - 2018.

Abstract

Introduction: Hashimoto's thyroiditis (HT) is an autoimmune disease that causes inflammation in the thyroid gland. Due to chronic inflammation, it has been linked to the development of papillary thyroid carcinoma (PTC). Objective: Determine if Hashimoto's thyroiditis is a poor prognostic factor in patients with papillary thyroid carcinoma, treated at the SOLCA Hospital, Guayaquil, 2014-2018.Materials and methods: The study is retrospective, relational and analytical. Results: We analyzed two groups, the first (A) constituted by patients with PTC and HT with a total of 94 patients, where the ages were between 12 - 85 years, with an average of 48, and the second (B) formed only by PTC with 122 patients, the mean age was 39 (range 12-76). In both groups it was evidenced that PTC prevails in the female sex, likewise, it was found that the most frequent histological variant of PTC is the classic or conventional variant (group A 74.5%; group B 83.6%), followed of the follicular variant (group A 14.9%; group B 11.5%). There were 3 relapses within the PTC + TH group and 25 relapses in the group that only suffered from PTC. Conclusions: We conclude that the presence of TH is not a poor prognostic factor for PTC. On the contrary, it could function as a factor related to a better evolution compared to PTC, since the recurrence rates were lower in them compared to those who had only PTC.