Factores de riesgo asociados a desarrollo de falla multiorgánica en pacientes con pancreatitis aguda en el Hospital Teodoro Maldonado Carbo. Enero 2018 – enero 2020.

Abstract

ABSTRACT Background: Acute Pancreatitis (AP) is a digestive and inflammatory disease of the pancreatic parenchyma; clinically manifested by severe epigastric pain and elevated pancreatic enzymes. Among its complications, Multi Organic Failure (MOF), a sudden, systemic clinical syndrome characterized by physiological deterioration capable of affecting more than one organic system, is the objective of this research. Objectives: To determine the presence of risk factors that allow predicting the development of MOF in patients with AP. Materials and methods: An observational, descriptive, longitudinal and retrospective study was carried out, including 330 patients with AP treated at the Teodoro Maldonado Carbo Hospital between January 2018 to January 2020, a representative sample of 180 patients was taken, analyzing the relationship between FMO and variables such as age, gender, hematocrit, BUN, and creatinine. Results: An age distribution was recorded in which the majority ranged from 31.21 to 69.11 years. No statistically significant differences [p => 0.05] were found between gender and development of MOF by means of the Chi-square test [p = 0.20]. Age showed a statistically significant difference superior in patients with MOF by means of Student's T [p = 0.004]. Greater significant differences were recorded in BUN [p = 0.000] and creatinine [p = 0.000] of the patients with MOF, while the hematocrit showed no relevant difference between both groups [p = 0.089]. Conclusions: MOF increases the mortality of BP, its development is associated with factors such as the patient's age, BUN and creatinine, while the hematocrit and gender did not show involvement in this phenomenon.