Complicaciones perinatales en hijos de pacientes con colestasis intrahepática del embarazo en el Hospital Alfredo G. Paulson de enero del 2018 a enero del 2021.

Abstract

Introduction: Intrahepatic cholestasis of pregnancy (ICP) occurs during the second and third trimester of pregnancy and it is characterized by palmar-plantar itching and elevation of bile acids. Although acute maternal manifestations of ICP are innocuous, it has been associated with high perinatal morbidity and mortality. Methodology: It is a prevalence study. Information was collected from the medical records of hospitalized patients at the Hospital Alfredo G. Paulson with a diagnosis of intrahepatic cholestasis of pregnancy from January 2018 to January 2021, and of the newborns who were hospitalized at Hospital Dr. Roberto Gilbert Elizalde for some perinatal complication. Results: There were 66.67% obstetric complications. The most prevalent is premature membrane rupture (PMR) with 33.33%, followed by risk of preterm delivery with 31.48%. The most prevalent neonatal complication is preterm delivery with 77.19% followed by respiratory distress in 50.88% and low birth weight in 45.61%. There was 1 case of the most feared complication, intrauterine fetal death (MFIU), which is equivalent to 1.85%. Conclusion: The most frequent perinatal complication is preterm delivery in 77.19% of cases. The main obstetric complications were premature rupture of membranes and threat of preterm delivery. The prevalence of neonatal morbidity and mortality is 82,46%.