Efectos de la disbiosis en la cavidad oral y su relación con la enfermedad de Parkinson. Revisión sistemática.

Abstract

Introduction: The imbalance in inflammatory mediators has formed the basis of the proposed link between oral dysbiosis and the development and progression of Parkinson's disease, the link between the two being "inflammation Objective: Determine the effects of dysbiosis in the oral cavity and its relationship with Parkinson's disease Materials and methods: Documentary bibliographic research, qualitative approach, retrospective in search, descriptive and analytical design, deductive method. Using peak analysis and keywords and mesh terms “Parkinson’s disease and Oral Dysbiosis”, “Inflammation and Parkinson’s, the search engines were used: Pubemed, Scielo, ELsevier. 1150 documents were reviewed, which, due to inclusion and exclusion criteria, were 68. Analysis and discussion of results: Several authors suggest that oral pathogens are involved in a process of neuroinflammation and the fall of the blood-brain barrier, which causes the onset or progression of Parkinson's disease according to some studies. Conclusion: Although the evidence should be stronger, many studies indicate that oral pathogens can initiate or be an adjunct to the progression of Parkinson's disease. In turn, this disease causes motor degeneration, which is why it affects oral hygiene, and these patients also use certain drugs that cause xerostomia, which is why they are more frequently affected by periodontal diseases.