Prevalencia de Carcinoma Hepatocelular en pacientes de 50 a 90 años con Cirrosis Hepática, en el Hospital Teodoro Maldonado Carbo, durante el periodo enero del 2018 a enero 2020.

Abstract

Introduction: Liver cirrhosis is a chronic pathology with considerable morbidity and mortality worldwide, It’s greatest complication is the development of hepatocellular carcinoma. Objective: To estimate the prevalence of Hepatocellular Carcinoma in patients 50 to 90 years old with liver cirrhosis at the Teodoro Maldonado Carbo Hospital during the period January 2018 to January 2020. Materials and Methods: A descriptive, observational, retrospective, cross-sectional study was carried out. Results: The prevalence of hepatocellular carcinoma in cirrhotic patients in this research was 12.31%, which corresponds to 33 patients of the 268 subjects considered for the study; It was evidenced that the mean age of the patients was 68.12 years; with a distribution according to gender with 60.6% male patients (n = 20) and 39.4% female patients (n = 13); The time elapsed in years between the diagnosis of cirrhosis and the appearance of cancer was 0 to 7 years, with the rate with the highest percentage of deaths being during the first year with 27.3%; Finally, the mortality of hepatocellular carcinoma was 78.8%. Conclusion: Liver cirrhosis is a disabling disease with a higher prevalence in males, throughout its development it can evolve into the complication with the worst prognosis, hepatocellular carcinoma, especially in patients with risk factors such as: Overweight, alcoholism, hepatitis B and C. becoming highly fatal, so it is necessary to improve diagnostic and therapeutic strategies.