Prevalencia de Nefritis Lúpica en pacientes de 18 a 40 años que acuden al Hospital Teodoro Maldonado Carbo durante el periodo del 1 de enero del 2018 al 31 de diciembre del 2020.

Abstract

Systemic lupus erythematosus is a pathology with an unpredictable and chronic course, one of the most frequent complications of this disease is lupus nephropathy, on average it appears after the first five years of having detected manifestations of SLE, most of them Patients present renal compromise at the time of renal biopsy despite the fact that many of them do not present clinical manifestations suggestive of renal compromise. Materials and methods: A study was carried out with a quantitative approach, of an observational, descriptive, retrospective, and cross-sectional type. Results: A sample of 114 was used. Of these, 91 (79.82%) were female and 23 (20.1%) were male. The average age in years in the female sex was 31.73 (IQR = 27-38), in the case of male patients, it was 30.09 (IQR = 25-35). According to the laboratory parameter of creatinine and the AKIN classification, the patients were categorized into their different stages. Where 100 (87.70%) patients were found in AKIN1. On the other hand, the 94 (82.4%) patients presented some comorbidity or underlying medical condition. Mortality in the HTMC was 131.57 per 1000 live births. Finally, it is evidenced that within class IV the largest number of patients was found, 43 (37.7%) patients were located in this stage. Conclusion: The lupus nephritic pathology of the patients who attended the HTMC presented with a higher prevalence in the female gender and in the third decade of life, the most prevalent histological class according to a real biopsy is class IV, finally, it was possible to show that the 82.4% of the patients with lupus nephritis presented comorbidities, of which the most prevalent was thyroid pathology with 26.6%.