Prevalencia de coinfección de Histoplasmosis y Criptococosis en pacientes VIH + en el Hospital de Infectología Dr. José Daniel Rodríguez Maridueña en el periodo de enero del 2020 a diciembre del 2020.

Abstract

INTRODUCTION. There are different types of coinfections that affect patients with HIV + among some of these are mycotic diseases. OBJECTIVE to calculate the prevalence of Histoplasmosis and Cryptococcosis in patients with HIV + and the concurrent infection that exists between these coinfections in the Infectology Hospital Dr. José Daniel Rodríguez Maridueña. POPULATION. We selected 619 patients from the Infectology Hospital of Guayaquil for the study METHOD. The research is a descriptive study of observational analysis and according to data collection it is a retrospective-cross-sectional study. RESULTS. The prevalence of HIV+ patients with cryptococcosis was 7% and histoplasmosis was 17.1%, average age with cryptococcosis coinfection was 34.2 years and histoplasmosis 36.2 years, the male sex with histoplasmosis was 81.1% and cryptococcosis 70.5%, the female sex with histoplasmosis was 18.9% and cryptococcosis 29.5%, the female sex with histoplasmosis was 18.9% and cryptococcosis 29.5%. 5%; patients with CD4 ≤ 200 were 57.4%; living patients were 78% and deceased were 22%; of 106 cases of histoplasmosis coinfection with CD4 ≤ 200 was 84.9%. and of 44 cases of cryptococcosis coinfection with CD4 ≤ 200 is 86.36%; the level of CD4 ≤ to 200 in living HIV + patients is 36. 34% and of deceased is 21 % CONCLUSION in this study the prevalence of cryptococcosis is 7.10% and of histoplasmosis is 17.10%, concurrent infection was 0.8%, gender most affected was male, the average age with cryptococcosis is 31 years and of histoplasmosis is 36. The most frequent coinfections were tuberculosis 35.9%, pneumonia 26%, toxoplasmosis 15%, meningitis 7.6%; CD4 ≤ 200 is more frequent with coinfection of cryptococcosis and histoplasmosis denoting that it is possible that it is a risk factor in relation to these variables and with the deceased patient.