“Quetiapina” Utilidad en trastornos conductuales en pacientes que reciben Cuidados Paliativos.

Abstract

Background: Neoplastic diseases have become a common pathology today, and its implications develop physical, psychiatric, behavioral and social disorders that affect patients and their families. The monotherapy treatment and combination therapy with Quetiapine (QTP) is effective and safe in patients receiving palliative care, improving their quality of life. Objective: To determine the pharmacological utility of QTP in the behavioral disorders of patients receiving Palliative Care. Methodology: Descriptive cross-sectional study carried out at the Solca-Guayaquil National Oncology Institute, in the outpatient clinic of Palliative Care, Psychiatry and Palliative Hospitalization, descriptive statistics were used analyzing the variables of age, sex, from October 2020 to July 2021. The GRADE system was used in order to optimize the quality of the evidence. Results: The association between the dependent variable of behavioral disorders with the utility of QTP is a p value of 0.03 with an OR of 4.737 and a confidence interval ranging from 1.555 to 14.429, which does not pass the unit for what so much is significant. Conclusions: QTP proved to be beneficial when assessed using the GRADE strategy, using the following question asked by the doctor directed to the patient or family member: when receiving a standardized QTP dose according to the type of disorder, how is the therapeutic response: good, partial or bad?, 41.7% presented a good answer, 44.6% a partial answer, and 13.5% a bad answer.