Correlación de los niveles séricos de alfa-fetoproteína y el tamaño tumoral en pacientes diagnosticados con carcinoma hepatocelular en el Hospital Teodoro Maldonado Carbo desde enero de 2019 a diciembre de 2020.

Abstract

Introduction: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, becoming one of the leading causes of cancer-related death worldwide. In Western countries around 80% of HCC cases are associated with cirrhosis secondary to chronic viral infections such as hepatitis B and C. Objective: To establish the correlation between serum levels of alpha fetoprotein and tumor size in patients diagnosed with hepatocellular carcinoma in Teodoro Maldonado Hospital from January 2019 to December 2020. Materials and Methods: Retrospective, observational, cross-sectional and analytical study. The data was obtained through a review of 262 medical records of patients diagnosed with hepatocellular carcinoma. Results: A single tumor was found in 168 patients (64.12%), while in 94 cases (35.88%) multiple tumors were present. 121 patients (46.18%) had a personal pathological history of cirrhosis, this being the most frequently presented. A correlation between serum alpha-fetoprotein levels and tumor size was confirmed (p = 0.0017). Likewise, mortality was found in 183 of the cases (69.85%). Conclusions: It was possible to demonstrate that there is a positive correlation between serum alpha fetoprotein levels and tumor size.