Efectos del tratamiento antirretroviral en la titulación de linfocitos T CD4 en pacientes gestantes diagnosticadas con VIH en el Hospital de Especialidades Teodoro Maldonado Carbo durante el periodo 2019-2021.

Abstract

The number of CD4 T lymphocyte in pregnant patients accompanied with a diagnosis of HIV can be affected when an adequate ARV regimen is not followed. When this condition exists, strict follow-up is necessary to improve the condition of the patient and her pregnancy. Therefore, treatment, CD4 T lymphocyte and viral load levels should be monitored in these patients and their response to them. Methodology: This is an observational, cross-sectional and descriptive study. It is necessary to use a synthetic analytical method to obtain clear and precise results within the research. Results: A considerable increase in the mean CD4 T lymphocyte was observed with an initial and final count of 575.40 % vs 612.26 % respectively, in addition, it was observed that at the end of pregnancy with ARV treatment 89.3% had an undetectable viral load. Most of the patients 81.43 % did not present adverse effects to the treatment. The percentage of patients with morbidities was low, with 5.71% of them having a threatened miscarriage. Conclusion: ARV treatment raises the mean number of CD4 T lymphocyte, and although this elevation does not seem to be directly related to viral load, it is noteworthy that patients with treatment reach undetectable values of this at the end of pregnancy.