Ancho de banda eritrocitaria y volumen medio plaquetario como predictores de mortalidad en pacientes diagnosticados con sepsis en el área de UCI del Hospital Naval de Guayaquil en el periodo 2018-2022.

Abstract

Sepsis is a pathology with a high mortality rate if not properly diagnosed and managed, its incidence is approximately 51.5 per 100,000 inhabitants. The pathophysiology of sepsis, together with the inflammatory process and oxidative stress reduce the survival of erythrocytes, preventing their maturation and inhibiting platelet maturation, which is believed to be related to the disease. Objective: To determine whether VMP and RDW are predictors of mortality in patients diagnosed with sepsis 72 hours after hospitalization in the ICU. Materials and methods: A retrospective cross-sectional descriptive observational study was carried out in 222 patients diagnosed with sepsis. Results: At 72 hours, 40.99% presented SCORE APACHE II >25pts with VMP >10fL, and 31.53% was related to higher mortality in patients admitted to the ICU with sepsis. 40.54% of patients with RDW>14.4% had SCORE APACHE II >25pts. And when relating the same variable with patient mortality, the results were that 30.18% of patients with RDW>14.4%. Conclusions: VMP and RDW are good predictors of mortality 72 hours after hospitalization in ICU in patients diagnosed with sepsis.