Valor predictivo de mortalidad de la Escala de Sofa en pacientes con septicemia ingresados en la UCIP del Hospital del Niño Dr. Francisco de Icaza Bustamante. periodo junio 2021 a junio del 2023.

Abstract

Introduction: Sepsis is one of the main health problems in the pediatric field due to its high morbidity and mortality. Currently, there are scales or scores to assess the mortality of sepsis, such as the SOFA, but its prognostic usefulness has not been evaluated in pediatric patients. Objective: To determine mortality according to the predictive value of the SOFA scale in patients with septicemia admitted to the PICU of the Dr. Francisco De Icaza Bustamante children's hospital during the period June 2021 - June 2023. Materials and methods: An observational, crosssectional, retrospective, and analytical study was carried out with the data provided by the statistics service from the Francisco Icaza Bustamante Pediatric Hospital. Of 96 patients, 75 met the inclusion criteria and 21 were excluded. Once the data was obtained, it was exported to the IBM SPSS Statistics version 29 application to carry out the statistical analysis. Results: A total of 47 patients (62.7%) died during their ICU stay and 28 (37.3%) patients were discharged alive. When performing the logistic regression analysis, it was observed that only the SOFA score at 48 hours is significant. Within its parameters, respiratory failure was the variable with the greatest association with mortality. Discussion: Different results were observed by Gogia P et al, who compared the SOFA at admission with that at 72h and found that the SOFA values in non-survivors were higher than those in survivors at both times. In contrast to our study, Lois A. et al. found a greater association with mortality to alterations in coagulation, the liver system and the central nervous system. Conclusion: The SOFA score at 48 hours of admission was found to be a strong predictor of mortality. In addition, other significant risk factors were identified, such as hypoxemia, creatinine elevations, arterial hypotension and use of vasoactive drugs, as well as thrombocytopenia.