Determinantes modificables y no modificables asociadas a complicaciones cardiometabólicas en niños y adolescentes con enfermedad renal crónica terminal atendidos en el hospital del niño Dr. Francisco De Icaza Bustamante período 2022 a 2023.

Abstract

Background: end-stage chronic kidney disease (CKD) constitutes the last phase of the disease where the kidneys cease their function, since the filtration and elimination of nitrogen, regulation of metabolism dependent on this organ, such as hydro-saline homeostasis, is not possible., acid-base balance, among others. In childhood and adolescence, disease-dependent complications arise, among which those related to electrolyte metabolism, hematological, cardiovascular, endocrinological and infectious are mentioned. Objective: determine the modifiable and non-modifiable factors associated with cardiovascular and metabolic complications in children and adolescents with chronic kidney disease. Materials and Methods study with a quantitative approach, non-experimental, cross-sectional, analytical and correlational design. The population and sample consisted of 46 patients. Results: factors related to cardiovascular and metabolic complications were identified; Among the first are the age group over 12 years, male, which had glomerulopathy as the cause; with chronic malnutrition, inadequate adherence to treatment, hemodialysis, uncontrolled hypertension and a longer duration of the pathology. Conclusions: there is a statistically significant association between the development of cardiovascular and metabolic complications with structural alterations as causal pathology and antihypertensive treatment, especially at supratherapeutic doses.