Impacto de la temporalidad de la trombólisis en las primeras dos horas frente a la tercera y cuarta hora, en pacientes con ictus isquémico, atendidos en el Hospital Teodoro Maldonado Carbo; junio 2022-junio 2024.

Abstract

Introduction: Cerebrovascular attack is the sudden loss of neurological function due to altered cerebral blood flow, due to an atherosclerotic process of the cerebral vasculature. For treatment, reperfusion therapies restore tissue oxygen supply, reduce disability and mortality, intravenous thrombolysis with rTPA is performed in appropriately selected patients, and the NIHSS scale to know the severity of the neurological condition and therapeutic management. Objective: To analyze the impact of the timing of Thrombolysis in the first two hours versus the third and fourth hours, in patients with Ischemic STROKE, treated at the Teodoro Maldonado Carbo Hospital; June 2022-June 2024. Methodology: The research design is Observational, Retrospective, Cross-sectional and Descriptive. Results: The prevalence of patients aged 58–67 years was 31.25%, with a male gender of 60.94% and 92.19% living in urban areas. Arterial hypertension accounted for 73.44%. 60.94% were treated within the third and fourth hour window, and 39.06% within the first and second hour. At admission, 65.62% had a moderate stroke NIHSS score (5–15), and at discharge, 51.56% had a mild stroke NIHSS score (1–4). 60.94% received treatment within 3–4 hours. 93.75% did not experience bleeding. Conclusions: Addressing modifiable risk factors and shortening the stroke–needle time had an impact proportional to the favorable outcome of patients' NIHSS scores at admission and discharge.