Procalcitonina como marcador temprano de neumonía asociada la ventilación mecánica invasiva, Unidad de Cuidados Intensivos Pediátricos, Hospital Roberto Gilbert, septiembre 2016 - febrero del 2017.

Abstract

Background:Pneumonia associated with Mechanical Ventilation is a frequent complication in Intensive Care Units, with the mostfrequent being 52%. The objective of this research is to evaluate the association that exists between Procalcitonin and patients diagnosed with Pneumoniaassociated with Mechanical Ventilation at the Roberto Gilbert Elizalde Pediatric Hospital in the city of Guayaquil. Materials and Methods: Observational, descriptive, prospective, longitudinal, analytical research; of relational level. The studypopulation was the total of patients admitted with non-infectious causes from September 2016 to February 2017. Results:The rate of pneumonia associated with mechanical ventilation was 28 per 1000 days of mechanical ventilation. Statistically significant differences were observed in the serum levels of Procalcitonin on days 2, 3, 4 (p <0.05). Using the ROC curves, it is concluded that the optimal cut-off value of Procalcitonin can be used as an early marker for the diagnosis of Pneumonia associated with Early Mechanical Ventilation is on day 2, with a value of1.1150 ng / ml, has a discriminative capacity of 78% with a sensitivity of 66.67% and a specificity of 84.48%. Its positive predictive value in 47.06%. Conclusions:Procalcitonin Sérica rise early in the pneumonia associated with mechanical ventilation, being better the determination on day two, presenting a low sensitivity, so it is not determinant to make an early diagnosis.