Comparación de criterios SOFA vs criterios SIRS como predictores de mortalidad en pacientes con sospecha de infección internados en la Unidad de Cuidados Intensivos en el Hospital General del Norte de Guayaquil los Ceibos entre enero del 2018 y enero del 2019.

Abstract

In this retrospective cross-sectional study, we analyzed the digital clinical histories of the patients who were hospitalized between 2018/01/01 and 2019/01/01 in the intensive care unit of the HGNGC, from which it was collected, among other variables , the SOFA Score and SIRS of each one at the time of admission to said unit in order to determine which of the two is a better predictor of mortality (during their stay in the ICU). After applying the exclusion criteria and eliminating subjects with insufficient data to establish reliable scores, 97 patients were obtained (56 men and 41 women, with age averages of 71.8 and 65 respectively). In total there were 31 patients who left alive and 66 died. The analysis of the data revealed through a T-Test of two variables that the SOFA Score was statistically significant (diff: -2.854; p = 0.0003; 95% CI), not the SIRS criteria, (diff: -0.389; p = 0.0517; 95% CI). Through logistic regression, an Odds Ratio (OR) of 1.27 (95% CI: 1.10 - 1.48; p = 0.001) and 1.67 (95% CI: 0.96 - 2.88; p = 0.065) for SOFA and SIRS respectively. In addition, a receiver operating characteristic curve (ROC) and its respective area under the curve (AUC) were constructed, which was larger in SOFA score with a value of 0.70 (95% CI; 0.59-0 , 81; p = 0.000), compared to SIRS that obtained a XIV value of 0.61 (95% CI; 0.47-0.72; p = 0.055). When applying the chi-squared calculation using Yates correction, the SIRS score obtained a value of 1.85 with a p = 0.17, while the SOFA score obtained a score of 8, 86 with a p = 0.002. As expected, the utility of the SOFA score for predicting mortality over the SIRS criteria in all statistical tools used, was ratified.