Beneficio del uso temprano de vasopresores en pacientes adultos diagnosticados con choque séptico en la Unidad de Emergencia del Hospital Teodoro Maldonado Carbo durante el año 2018 hasta el 2020.

Abstract

Introduction: Septic shock is a state where the deregulated response of the host to an infection leads to organ failure. In the early stage of the shock it can be reversed if it is aggressively treated with fluid therapy and vasopressors. Early initiation of vasopressor therapy has been shown to play an important role in controlling shock and reducing mortality. Methodology: Observational study (descriptive, analytical, retrospective) of cross-sectional design. 150 patients met the inclusion criteria and made up the study sample. Results: A higher prevalence was observed in males (62.6%) than in females (37.33%), in those over 65 years of age (64.67%) than in those under this age (35.33%). The three main comorbidities were high blood pressure (57.33%), type II diabetes mellitus (30.67%) and non dialysis chronic kidney disease (18%). The most used vasopressor was norepinephrine (73.33%) which was not associated with mortality in the emergency (p = 0.133); in most users (94.12%) early vasopressor support was used (<= 60 minutes) without being significantly associated with the discharge condition (p = 0.572); the duration of this greater than 18-24 hours was not related to mortality (p = 0.636). A causal relationship between the SOFA score at admission and the discharge condition was evidenced (p = 0.011). Conclusion: The early use of vasopressor therapy (less than or equal to 60 minutes) was not associated with decreased mortality in these patients.